/* /medicamento/x — ficha del fármaco v2 (04/11/2026) */
.mddv2{font-family:'Nunito',system-ui,sans-serif;background:linear-gradient(180deg,#f5f8ff 0%,#fff 70%);padding-bottom:50px;color:#0f172a}
.hv2.mddv2 .mddv2-hero{padding:34px 0 110px;min-height:0}
.mddv2-back{display:flex;width:max-content;align-items:center;gap:8px;color:#fff;font-weight:800;text-decoration:none;opacity:.9;margin-bottom:14px;position:relative;z-index:10}
.mddv2-back:hover{color:#ffd23f;opacity:1}
.hv2.mddv2 .hero-badge i{margin-right:4px}
.hv2.mddv2 .hero-title{font-size:clamp(2.1rem,4.4vw,3.2rem);font-weight:900;margin-bottom:10px;overflow-wrap:anywhere}
.hv2.mddv2 .hero-title em{font-size:.62em}
.hv2.mddv2 .hero-subtitle{max-width:760px;margin-bottom:14px}
.mddv2-chips{display:flex;flex-wrap:wrap;gap:8px;margin-bottom:18px}
.mddv2-chips span{background:rgba(255,255,255,.16);border:1px solid rgba(255,255,255,.3);color:#fff;border-radius:50px;padding:5px 12px;font-weight:800;font-size:.85rem}
.mddv2-chips span.tg{background:#ffd23f;border-color:#ffd23f;color:#3b2a00}
.mddv2-hero-cta{display:flex;flex-wrap:wrap;gap:10px;position:relative;z-index:10}

.mddv2-btn{display:inline-flex;align-items:center;justify-content:center;gap:8px;border:0;border-radius:50px;padding:11px 22px;font-weight:900;font-family:inherit;text-decoration:none;cursor:pointer;background:linear-gradient(135deg,#1f5cff,#7a2cff);color:#fff;box-shadow:0 14px 28px -16px rgba(31,92,255,.9)}
.mddv2-btn:hover{color:#fff;filter:brightness(1.06)}
.mddv2-btn.light{background:#fff;color:#1f3a8a;box-shadow:none}
.mddv2-btn.light:hover{color:#1f5cff}
.mddv2-btn.ghost{background:rgba(255,255,255,.14);border:1px solid rgba(255,255,255,.45);box-shadow:none}
.mddv2-btn.full{width:100%;margin-top:12px}

.mddv2-body{margin-top:-70px;position:relative;z-index:5}
.mddv2-card{background:#fff;border:1px solid #e8edf5;border-radius:24px;box-shadow:0 24px 50px -36px rgba(15,23,42,.5);padding:20px 22px;margin-bottom:16px}
.mddv2-card h2{font-size:1.1rem;font-weight:900;margin:0 0 12px;display:flex;align-items:center;gap:9px}
.mddv2-card h2 i{color:#1f5cff}
.mddv2-card h3{font-size:.78rem;font-weight:900;text-transform:uppercase;letter-spacing:.04em;color:#64748b;margin:16px 0 8px}
.mddv2-card .txt{color:#334155;font-weight:600;line-height:1.65;margin:0}
.mddv2-head{display:flex;justify-content:space-between;align-items:center;gap:10px;flex-wrap:wrap;margin-bottom:12px}
.mddv2-head h2{margin:0}
.mddv2-counts{display:flex;gap:6px;flex-wrap:wrap}
.mddv2-counts b{background:#dcfce7;color:#166534;border-radius:50px;padding:3px 10px;font-size:.78rem;font-weight:900}
.mddv2-counts b.es{background:#fff7e6;color:#92400e}
.mddv2-pending{margin:10px 0 0;background:#f8faff;color:#475569;border-radius:12px;padding:8px 12px;font-weight:700;font-size:.85rem}
.mddv2-hint{margin:12px 0 0;color:#64748b;font-weight:700;font-size:.84rem}

/* Aprobación */
.mddv2-approval{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;margin-bottom:12px}
.mddv2-approval .ap{background:#fff;border:1px solid #e8edf5;border-top:5px solid #cbd5e1;border-radius:20px;padding:14px 16px;box-shadow:0 24px 50px -36px rgba(15,23,42,.5)}
.mddv2-approval .ap.ok{border-top-color:#16a34a}.mddv2-approval .ap.mid{border-top-color:#f59e0b}.mddv2-approval .ap.no{border-top-color:#ef4444}
.mddv2-approval .rg{display:block;font-size:.74rem;font-weight:900;text-transform:uppercase;letter-spacing:.04em;color:#64748b}
.mddv2-approval b{display:block;font-weight:900;font-size:1rem;margin-top:2px}
.mddv2-approval .ap.na b{color:#94a3b8}
.mddv2-approval small{display:block;color:#475569;font-weight:700;font-size:.82rem;margin-top:2px}
.mddv2-esnote{display:flex;gap:8px;background:#fff7e6;color:#78350f;border-radius:16px;padding:10px 14px;font-weight:800;font-size:.88rem;margin:0 0 16px}

.mddv2-grid{display:grid;grid-template-columns:minmax(0,1.65fr) minmax(0,1fr);gap:16px;align-items:start}

.mddv2-tags{display:flex;flex-wrap:wrap;gap:6px}
.mddv2-tags a{background:linear-gradient(135deg,#1f5cff,#7a2cff);color:#fff;border-radius:50px;padding:5px 12px;font-weight:900;font-size:.84rem;text-decoration:none}
.mddv2-tags a:hover{color:#fff;filter:brightness(1.08)}
.mddv2-effects{display:flex;flex-wrap:wrap;gap:6px}
.mddv2-effects span{background:#fff7e6;border:1px solid #fde68a;color:#78350f;border-radius:50px;padding:5px 12px;font-weight:800;font-size:.85rem}

.mddv2-trials{display:flex;flex-direction:column;gap:8px}
.mddv2-trial{position:relative;display:block;border:1px solid #eef2f7;border-radius:18px;padding:12px 40px 12px 14px;text-decoration:none;color:inherit;transition:border-color .15s,background .15s}
.mddv2-trial:hover{border-color:#c7d6ff;background:#f8faff;color:inherit}
.mddv2-trial .tt{display:block;font-weight:800;font-size:.93rem;line-height:1.35}
.mddv2-trial .meta{display:flex;flex-wrap:wrap;gap:6px;align-items:center;margin-top:6px}
.mddv2-trial code{color:#64748b;font-size:.76rem;background:none;padding:0;font-weight:700}
.mddv2-trial .b{background:#f1f5f9;color:#475569;border-radius:50px;padding:2px 9px;font-size:.74rem;font-weight:800}
.mddv2-trial .b.ok{background:#dcfce7;color:#166534}.mddv2-trial .b.mid{background:#eef3ff;color:#1f3a8a}.mddv2-trial .b.es{background:#fff7e6;color:#92400e}
.mddv2-trial small{display:block;color:#64748b;font-weight:700;font-size:.78rem;margin-top:5px}
.mddv2-trial .go{position:absolute;right:14px;top:50%;transform:translateY(-50%);color:#94a3b8}

.mddv2-facts{margin:0;display:flex;flex-direction:column}
.mddv2-facts div{display:flex;justify-content:space-between;gap:12px;padding:8px 0;border-bottom:1px dashed #eef2f7}
.mddv2-facts div:last-child{border-bottom:0}
.mddv2-facts dt{color:#64748b;font-weight:800;font-size:.86rem}
.mddv2-facts dd{margin:0;font-weight:900;font-size:.9rem;text-align:right}
.mddv2-facts dd small{display:block;color:#15803d;font-weight:800}
.mddv2-links{display:flex;flex-direction:column;gap:6px}
.mddv2-links a{display:flex;justify-content:space-between;align-items:center;gap:10px;border:1px solid #eef2f7;border-radius:14px;padding:9px 12px;text-decoration:none;color:inherit}
.mddv2-links a:hover{border-color:#c7d6ff;background:#f8faff;color:inherit}
.mddv2-links span{min-width:0}
.mddv2-links b{display:block;font-weight:900;font-size:.9rem}
.mddv2-links small{display:block;color:#64748b;font-weight:700;font-size:.76rem;overflow-wrap:anywhere}
.mddv2-links em{font-style:normal;color:#1f5cff;font-weight:900;font-size:.78rem;white-space:nowrap;text-align:right}
.mddv2-warn{background:#fffbeb;border-color:#fde68a}
.mddv2-warn h2 i{color:#d97706}
.mddv2-warn p{margin:0;color:#78350f;font-weight:700;font-size:.86rem;line-height:1.55}

@media(max-width:991px){.mddv2-grid{grid-template-columns:minmax(0,1fr)}}
@media(max-width:575px){
  .mddv2-card{padding:16px 14px}
  .mddv2-approval{grid-template-columns:minmax(0,1fr);gap:8px}
  .mddv2-approval .ap{display:grid;grid-template-columns:auto 1fr;column-gap:10px;align-items:baseline;padding:12px 14px}
  .mddv2-approval .rg{grid-row:span 2;min-width:96px}
  .mddv2-hero-cta .mddv2-btn{flex:1;padding:10px 14px;white-space:nowrap}
  .mddv2-links em{white-space:normal}
}